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A regulatory module controlling stress-induced cell cycle arrest in Arabidopsis
http://hdl.handle.net/10061/13132
http://hdl.handle.net/10061/13132d7c2ee47-c7f6-488e-b81b-d9a8e42e6f5f
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2019-04-11 | |||||
| タイトル | ||||||
| タイトル | A regulatory module controlling stress-induced cell cycle arrest in Arabidopsis | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | cell cycle arrest | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | DNA damage | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | heat stress | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | transcription factors | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | protein stability | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | gene expression | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | open access | |||||
| 著者 |
Takahashi, Naoki
× Takahashi, Naoki× Ogita, Nobuo× Takahashi, Tomonobu× Taniguchi, Shoji× Tanaka, Maho× Seki, Motoaki× Umeda, Masaaki |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Cell cycle arrest is an active response to stresses that enables organisms to survive under fluctuating environmental conditions. While signalling pathways that inhibit cell cycle progression have been elucidated, the putative core module orchestrating cell cycle arrest in response to various stresses is still elusive. Here we report that in Arabidopsis, the NAC-type transcription factors ANAC044 and ANAC085 are required for DNA damage-induced G2 arrest. Under genotoxic stress conditions, ANAC044 and ANAC085 enhance protein accumulation of the R1R2R3-type Myb transcription factor (Rep-MYB), which represses G2/M-specific genes. ANAC044/ANAC085-dependent accumulation of Rep-MYB and cell cycle arrest are also observed in the response to heat stress that causes G2 arrest, but not to osmotic stress that retards G1 progression. These results suggest that plants deploy the ANAC044/ANAC085-mediated signalling module as a hub which perceives distinct stress signals and leads to G2 arrest. | |||||
| 書誌情報 |
en : eLife 巻 8, 発行日 2019-04-04 |
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| artnum | ||||||
| 値 | e43944 | |||||
| 出版者 | ||||||
| 出版者 | eLife Sciences Publications, Ltd | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2050-084X | |||||
| PubMed番号 | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 30944065 | |||||
| 出版者版DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.7554/eLife.43944 | |||||
| 権利 | ||||||
| 権利情報 | c 2019, Takahashi et al. | |||||
| 権利 | ||||||
| 権利情報 | This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
