WEKO3
アイテム
{"_buckets": {"deposit": "c82aa618-7f91-4ec2-8e40-b994260cb8d2"}, "_deposit": {"created_by": 4, "id": "9198", "owners": [4], "pid": {"revision_id": 0, "type": "depid", "value": "9198"}, "status": "published"}, "_oai": {"id": "oai:naist.repo.nii.ac.jp:00009198", "sets": ["44"]}, "author_link": ["24314", "132"], "item_7_biblio_info_9": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2015-05-29", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "8", "bibliographicPageEnd": "646", "bibliographicPageStart": "636", "bibliographicVolumeNumber": "20", "bibliographic_titles": [{"bibliographic_title": "Genes to Cells", "bibliographic_titleLang": "en"}]}]}, "item_7_description_7": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Plants use various mechanisms to cope with environmental stresses, which often threaten genome integrity. In Arabidopsis, DNA double-strand breaks (DSBs) reduce root meristem size in a SOG1-dependent manner. SOG1 is a key transcription factor controlling the response to DNA damage. However, the underlying mechanism remains largely unknown. In this study, we found that treatment with the DSB inducer zeocin increased the accumulation of H2O2 in root tips. Chromatin immunoprecipitation analysis showed that SOG1 directly binds to the promoter of FMO1, which encodes a flavin-containing monooxygenase and is associated with the production of reactive oxygen species (ROS), H2O2 in particular. Indeed, zeocin induced the expression of FMO1 in a SOG1-dependent manner, and neither the sog1 nor the fmo1 knockout mutant exhibited higher H2O2 accumulation in root tips. Consequently, both sog1 and fmo1 could tolerate exposure to zeocin, in terms of root growth and the maintenance of the meristem size. However, transgenic plants over-expressing FMO1 also accumulated H2O2 in response to zeocin exposure, suggesting that other ROS-synthesis genes are also involved in the regulation of ROS production. We conclude that SOG1-mediated regulation of ROS homeostasis plays a key role in the reduction of root meristem size under DNA stress conditions.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_7_publisher_10": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Wiley", "subitem_publisher_language": "en"}]}, "item_7_relation_15": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "26033196", "subitem_relation_type_select": "PMID"}}]}, "item_7_relation_17": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1111/gtc.12255", "subitem_relation_type_select": "DOI"}}]}, "item_7_rights_18": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "c 2015 The Molecular Biology Society of Japan and Wiley Publishing Asia Pty Ltd", "subitem_rights_language": "en"}, {"subitem_rights": "This is the peer reviewed version of the following article: [Genes to Cells, 20(8):636-646], which has been published in final form at [https://doi.org/10.1111/gtc.12255]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.", "subitem_rights_language": "en"}]}, "item_7_source_id_12": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1356-9597", "subitem_source_identifier_type": "ISSN"}]}, "item_7_source_id_14": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA11078945", "subitem_source_identifier_type": "NCID"}]}, "item_7_text_25": {"attribute_name": "NAIST ID", "attribute_value_mlt": [{"subitem_text_value": "73290587"}]}, "item_7_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Chen, Poyu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "24314", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Umeda, Masaaki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "132", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "80221810", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=80221810"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2023-03-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "10.1111_gtc.12255.pdf", "filesize": [{"value": "7.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 7500000.0, "url": {"label": "fulltext", "objectType": "fulltext", "url": "https://naist.repo.nii.ac.jp/record/9198/files/10.1111_gtc.12255.pdf"}, "version_id": "59b23554-a44d-46ea-8f7b-f45c7f7b9a24"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size in Arabidopsis thaliana", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size in Arabidopsis thaliana", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "4", "path": ["44"], "permalink_uri": "http://hdl.handle.net/10061/12587", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2018-10-05"}, "publish_date": "2018-10-05", "publish_status": "0", "recid": "9198", "relation": {}, "relation_version_is_last": true, "title": ["DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size in Arabidopsis thaliana"], "weko_shared_id": -1}
DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size in Arabidopsis thaliana
http://hdl.handle.net/10061/12587
http://hdl.handle.net/10061/12587ec6092ac-4508-4761-944c-0f7cd1e80eaf
名前 / ファイル | ライセンス | アクション |
---|---|---|
![]() |
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2018-10-05 | |||||
タイトル | ||||||
タイトル | DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size in Arabidopsis thaliana | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
著者 |
Chen, Poyu
× Chen, Poyu× Umeda, Masaaki |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Plants use various mechanisms to cope with environmental stresses, which often threaten genome integrity. In Arabidopsis, DNA double-strand breaks (DSBs) reduce root meristem size in a SOG1-dependent manner. SOG1 is a key transcription factor controlling the response to DNA damage. However, the underlying mechanism remains largely unknown. In this study, we found that treatment with the DSB inducer zeocin increased the accumulation of H2O2 in root tips. Chromatin immunoprecipitation analysis showed that SOG1 directly binds to the promoter of FMO1, which encodes a flavin-containing monooxygenase and is associated with the production of reactive oxygen species (ROS), H2O2 in particular. Indeed, zeocin induced the expression of FMO1 in a SOG1-dependent manner, and neither the sog1 nor the fmo1 knockout mutant exhibited higher H2O2 accumulation in root tips. Consequently, both sog1 and fmo1 could tolerate exposure to zeocin, in terms of root growth and the maintenance of the meristem size. However, transgenic plants over-expressing FMO1 also accumulated H2O2 in response to zeocin exposure, suggesting that other ROS-synthesis genes are also involved in the regulation of ROS production. We conclude that SOG1-mediated regulation of ROS homeostasis plays a key role in the reduction of root meristem size under DNA stress conditions. | |||||
書誌情報 |
en : Genes to Cells 巻 20, 号 8, p. 636-646, 発行日 2015-05-29 |
|||||
出版者 | ||||||
出版者 | Wiley | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1356-9597 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 26033196 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1111/gtc.12255 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11078945 | |||||
権利 | ||||||
権利情報 | c 2015 The Molecular Biology Society of Japan and Wiley Publishing Asia Pty Ltd | |||||
権利 | ||||||
権利情報 | This is the peer reviewed version of the following article: [Genes to Cells, 20(8):636-646], which has been published in final form at [https://doi.org/10.1111/gtc.12255]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | |||||
著者版フラグ | ||||||
出版タイプ | AM |