| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2026-02-10 |
| タイトル |
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タイトル |
Cellular energy sensor SnRK1 suppresses salicylic acid-dependent and -independent defenses and bacterial resistance in Arabidopsis |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
open access |
| 著者 |
Jie, Linnan
Sanagi, Miho
安田, 盛貴
Yamada, Kohji
Ejima, Saki
Sugisaki, Ayumi
Takagi, Junpei
Nomoto, Mika
Xin, Xiu-Fang
Tada, Yasuomi
西條, 雄介
Sato, Takeo
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
In nature, plants cope with various pathogens that compete for cellular resources during infection. It has long been suggested that plant defense activity must be linked to cellular energy and metabolic states to optimize the balance between growth and defense. However, the molecular mechanisms that regulate immune activity in relation to cellular energy status remain unclear. Here, we demonstrate that the plant energy sensor SNF1-RELATED KINASE 1 (SnRK1) plays a critical role in modulating defense responses and bacterial resistance in Arabidopsis thaliana. Bacterial elicitor-induced expression of defense marker genes, such as PATHOGENESIS-RELATED 1 (PR1), is significantly repressed under sugar-limited conditions in wild-type seedlings, whereas this expression is markedly enhanced in the snrk1α1i/α2 knockdown mutants. SnRK1 restricts defense-related gene expression and resistance to the biotrophic bacterial pathogen Pseudomonas syringae pv. tomato DC3000, which are partly dependent on salicylic acid (SA). In addition, we found that the SnRK1 kinase activity is increased by high humidity. Consistently, SnRK1 is critical for the suppression of SA-mediated defense responses under high humidity conditions. SnRK1 physically associates with the SA-related transcription factors TGACG SEQUENCE-SPECIFIC BINDING PROTEIN 4 (TGA4) and TGA2 to attenuate PR1 expression. These findings provide valuable insight into the molecular mechanisms linking cellular energy status with immune regulation in plants. |
| 書誌情報 |
en : Proceedings of the National Academy of Sciences
巻 122,
号 48,
p. 1-10,
ページ数 10,
発行日 2025-11-26
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| 出版者 |
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出版者 |
National Academy of Sciences |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
1091-6490 |
| 出版者版DOI |
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関連タイプ |
isReplacedBy |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1073/pnas.2527765122 |
| 出版者版URI |
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関連タイプ |
isReplacedBy |
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識別子タイプ |
URI |
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関連識別子 |
https://www.pnas.org/doi/abs/10.1073/pnas.2527765122 |
| 権利 |
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権利情報Resource |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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権利情報 |
Copyright © 2025 the Author(s). Published by PNAS.This article is distributed under Creative CommonsAttribution- NonCommercial-NoDerivatives License 4.0(CC BY- NC- ND). |
| 著者版フラグ |
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出版タイプ |
NA |
| 助成情報 |
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助成機関名 |
Japan Society for the Promotion of Science (JSPS) |
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研究課題番号 |
23H02170 |
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研究課題番号URI |
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K26863/ |
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研究課題名 |
糖による植物免疫強化機構の解明 |
| 助成情報 |
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助成機関名 |
Japan Society for the Promotion of Science (JSPS) |
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研究課題番号 |
23H04184 |
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研究課題番号URI |
https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-23H04184/ |
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研究課題名 |
不規則な栄養環境おける植物ステージゲート機構 |
| 助成情報 |
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助成機関名 |
Japan Society for the Promotion of Science (JSPS) |
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研究課題番号 |
25H01346 |
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研究課題番号URI |
https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-25H01346/ |
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研究課題名 |
植物のシンプラスト栄養輸送を介した個体成長統御機構 |
| 助成情報 |
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助成機関名 |
Japan Society for the Promotion of Science (JSPS) |
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研究課題番号 |
23K13921 |
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研究課題番号URI |
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K13921/ |
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研究課題名 |
植物の栄養環境に応じた花成と代謝の協調的制御機構の解明 |
| 助成情報 |
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助成機関名 |
Japan Society for the Promotion of Science (JSPS) |
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研究課題番号 |
21K14829 |
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研究課題番号URI |
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K14829/ |
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研究課題名 |
高湿度環境におけるアブシジン酸を介した植物-病原細菌間相互作用の解明 |
| 助成情報 |
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助成機関名 |
Japan Society for the Promotion of Science (JSPS) |
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研究課題番号 |
18H02467 |
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研究課題番号URI |
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18H02467/ |
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研究課題名 |
栄養環境情報と微生物情報の統合に基づく植物免疫応答の制御 |
| 助成情報 |
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助成機関名 |
Japan Society for the Promotion of Science (JSPS) |
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研究課題番号 |
21H02507 |
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研究課題番号URI |
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21H02507/ |
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研究課題名 |
湿度環境情報に基づく植物免疫応答の制御 |
| 助成情報 |
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助成機関名 |
Japan Society for the Promotion of Science (JSPS) |
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研究課題番号 |
20H05905 |
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研究課題番号URI |
https://kaken.nii.ac.jp/grant/KAKENHI-ORGANIZER-20H05905/ |
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研究課題名 |
不均一環境変動に対する植物のレジリエンスを支える多層的情報統御の分子機構 |
| 助成情報 |
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助成機関名 |
Japan Society for the Promotion of Science (JSPS) |
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研究課題番号 |
20H05906 |
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研究課題番号URI |
https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-20H05906/ |
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研究課題名 |
植物の不均一環境変動へのレジリエンスを支える転写開始点制御機構 |
| 助成情報 |
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助成機関名 |
Japan Science and Technology Agency (JST) |
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研究課題番号 |
JPMJAX22BN |
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研究課題名 |
ACT-X |
| 助成情報 |
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助成機関名 |
China Scholarship Council |
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研究課題番号 |
201906350019 |
| 助成情報 |
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助成機関名 |
Hokkaido University |
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研究課題名 |
Hokkaido University Young Scientist Support Program |
