| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-11-13 |
| 日付 |
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日付 |
2026-08-18 |
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日付タイプ |
Available |
| タイトル |
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タイトル |
Synergistic Effects of Astaxanthin and Chlorophyll a on Singlet Oxygen Quenching Reinforced by Calcium Ascorbate |
| 言語 |
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言語 |
eng |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Astaxanthin |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Calcium Ascorbate |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Chlorophyll A |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Oxidation−Reduction Potential |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Quenching Rate |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Singlet Oxygen |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Antioxidants |
| キーワード |
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主題Scheme |
Other |
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主題 |
Fluorescence |
| キーワード |
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主題Scheme |
Other |
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主題 |
Mixtures |
| キーワード |
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主題Scheme |
Other |
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主題 |
Quenching |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Toxicological synergy |
| 資源タイプ |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
embargoed access |
| 著者 |
Yamada, Magohei
Matsuhira, Takashi
Yamamoto, Keizo
Asanoma, Fumio
森本, 積
河合, 壯
Sakai, Hiromi
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
This study examines the synergistic effects of astaxanthin and chlorophyll a in quenching singlet oxygen (1O2). The 1O2 quenching rate constant of chlorophyll a is 1.72 × 1010 M–1 s–1, but it increases to 3.17 × 1010 M–1 s–1 in the presence of astaxanthin. The strongest synergistic effect occurs at a molar ratio of astaxanthin:chlorophyll a = 1:2. 1H NMR analysis revealed shifts in signals and changes in the longitudinal relaxation time (T1) of astaxanthin upon the addition of chlorophyll a, indicating their proximity and interaction, which were also supported by fluorescence quenching analysis. Further addition of 150 equimolar calcium ascorbate protects more than 95% of both antioxidants from thermal decomposition (60 °C, 1 h). The optimal molar ratio of astaxanthin, chlorophyll a, and calcium ascorbate is 1:2:150, maximizing the synergistic effect of astaxanthin and chlorophyll a, while calcium ascorbate reinforces 1O2 quenching by providing a reductive environment and long-term stability. |
| 書誌情報 |
en : ACS Food Science & Technology
巻 5,
号 9,
p. 3307-3316,
ページ数 10,
発行日 2025-08-18
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| 出版者 |
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出版者 |
American Chemical Society |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
2692-1944 |
| 出版者版DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1021/acsfoodscitech.5c00260 |
| 出版者版URI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
URI |
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|
関連識別子 |
https://pubs.acs.org/doi/full/10.1021/acsfoodscitech.5c00260 |
| 権利 |
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権利情報 |
© 2025 American Chemical Society. This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Food Science & Technology, copyright c 2025 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acsfoodscitech.5c00260 . 出版社許諾条件により、本文は2026年8月18日以降に公開。 |
| 著者版フラグ |
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出版タイプ |
AM |
| 助成情報 |
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助成機関名 |
Japan Society for the Promotion of Science (JSPS) |
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研究課題番号 |
22K12824 |
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研究課題番号URI |
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K12824/ |
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研究課題名 |
リポソーム化した複合抗酸化剤による人工赤血球のメト化抑制とその機構の解明 |
| 助成情報 |
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助成機関名 |
Ministry of Education, Culture, Sports, Science and Technology (MEXT) |
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研究課題名 |
Advanced Research Infrastructure for Materials and Nanotechnology (ARIM) |
| 助成情報 |
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助成機関名 |
Nara Medical University and Nara Institute of Science and Technology |
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研究課題名 |
Joint Research Grant Program with Nara Institute of Science and Technology (Nara Medical University Grant) |
fulltext (3.6 MB)
