| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-09-10 |
| タイトル |
|
|
タイトル |
Shape-Modified Ultrathin Glass Sheet Cantilever for Precise Single Cell Stiffness Measurement |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Amorphous materials |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Manufacturing |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Sensors |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Stiffness |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Thickness |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
ultrathin glass sheet |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
cantilever sensors |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Young’s modulus |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
cell property |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
cell stiffness |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
femtosecond laser |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
| 著者 |
Yuan, Yapeng
Lyu, Chaoyang
Ota, Nobutoshi
Li, Ming
Lei, Cheng
細川, 陽一郎
Tanaka, Yo
Yang, Yang
Yalikun, Yaxiaer
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Due to its small size, label-free nature, and excellent compatibility with surrounding instruments, the microcantilever-based sensor is widely used in physical, chemical, and biological measurements. However, traditional microcantilevers face limitations due to complex fabrication methods, intricate operating procedures, or low sensitivity. In this research, we propose a shape-modified, 10 μm ultrathin glass sheet (UTGS)-based cantilever that is highly sensitive (nN/μm) and flexible, integrated with a strain gauge sensor. We present its application in measuring the mechanical properties of single cells. Compared with conventional methods, the proposed UTGS-based cantilever is easier to fabricate, offers superior physical and chemical properties, and demonstrates a high linear correlation between voltage change and applied force or displacement. The cantilever has a sensitivity of 190 nN/μm, making it suitable for measuring the cell stiffness. Additionally, it exhibits excellent optical transparency, enabling real-time observation during measurements, as demonstrated in the stiffness measurement of Dictyostelium cells. |
| 書誌情報 |
en : ACS Measurement Science Au
巻 5,
号 3,
p. 277-286,
ページ数 10,
発行日 2024-12-04
|
| 出版者 |
|
|
出版者 |
American Chemical Society |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2694-250X |
| 出版者版DOI |
|
|
関連タイプ |
isReplacedBy |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1021/acsmeasuresciau.4c00074 |
| 出版者版URI |
|
|
関連タイプ |
isReplacedBy |
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://pubs.acs.org/doi/10.1021/acsmeasuresciau.4c00074 |
| 権利 |
|
|
権利情報Resource |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
権利情報 |
Copyright © 2024 The Authors. Published by American Chemical Society. This publication is licensed under CC-BY-NC-ND 4.0 . |
| 著者版フラグ |
|
|
出版タイプ |
NA |
| 助成情報 |
|
|
|
助成機関名 |
National Natural Science Foundation of China |
|
|
研究課題番号 |
42222606 |
| 助成情報 |
|
|
|
助成機関名 |
National Natural Science Foundation of China |
|
|
研究課題番号 |
62103400 |
| 助成情報 |
|
|
|
助成機関名 |
National Natural Science Foundation of China |
|
|
研究課題番号 |
42211540003 |
| 助成情報 |
|
|
|
助成機関名 |
Amada Foundation |
| 助成情報 |
|
|
|
助成機関名 |
NSG Foundation |
