| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2024-10-16 |
| タイトル |
|
|
タイトル |
A fungal sesquiterpene biosynthesis gene cluster critical for mutualist-pathogen transition in Colletotrichum tofieldiae |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
| 著者 |
晝間, 敬
Aoki, Seishiro
Takino, Junya
Higa, Takeshi
Utami, Yuniar Devi
Shiina, Akito
Okamoto, Masanori
Nakamura, Masami
Kawamura, Nanami
Ohmori, Yoshihiro
Sugita, Ryohei
Tanoi, Keitaro
Sato, Toyozo
Oikawa, Hideaki
Minami, Atsushi
Iwasaki, Wataru
西條, 雄介
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Plant-associated fungi show diverse lifestyles from pathogenic to mutualistic to the host; however, the principles and mechanisms through which they shift the lifestyles require elucidation. The root fungus Colletotrichum tofieldiae (Ct) promotes Arabidopsis thaliana growth under phosphate limiting conditions. Here we describe a Ct strain, designated Ct3, that severely inhibits plant growth. Ct3 pathogenesis occurs through activation of host abscisic acid pathways via a fungal secondary metabolism gene cluster related to the biosynthesis of sesquiterpene metabolites, including botrydial. Cluster activation during root infection suppresses host nutrient uptake-related genes and changes mineral contents, suggesting a role in manipulating host nutrition state. Conversely, disruption or environmental suppression of the cluster renders Ct3 beneficial for plant growth, in a manner dependent on host phosphate starvation response regulators. Our findings indicate that a fungal metabolism cluster provides a means by which infectious fungi modulate lifestyles along the parasitic$2013mutualistic continuum in fluctuating environments. |
| 書誌情報 |
en : Nature Communications
巻 14,
号 1,
発行日 2023-09-06
|
| 出版者 |
|
|
出版者 |
Nature Research |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2041-1723 |
| 出版者版DOI |
|
|
関連タイプ |
isReplacedBy |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1038/s41467-023-40867-w |
| 出版者版URI |
|
|
関連タイプ |
isReplacedBy |
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://www.nature.com/articles/s41467-023-40867-w |
| 権利 |
|
|
権利情報Resource |
http://creativecommons.org/licenses/by/4.0/ |
|
権利情報 |
$00A9 The Author(s) 2023 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
| 著者版フラグ |
|
|
出版タイプ |
NA |
